General Criteria for Pipette Tips

In 1958, the German company Eppendorf invented the first single-channel fixed-range pipette. In 1968, the Finnish Lab system (Raybo) invented a multi-channel fixed-range pipette, which greatly improved the efficiency of pipetting operations. In the early 1970s, Gilson of France introduced the first single-channel adjustable-range pipette and named it Pipetman.

Later, in the late 1970s, Gilson modified it to make the suction/discharge button and the ejection button independent of each other. In the 1980s, Danish CAPP launched a semi-sterilizable, all-metal, high-precision pipette, and Eppendorf launched the Reference series, which can sterilize the entire pipette. In 1984, the United States RAININ (Raining) began to let the world’s human body experience the thrill of electric pipettes. In 2000, the Danish cap launched the world’s only 64-channel high-precision pipette.

Classification working principle: whether the built-in piston / external piston range is adjustable: adjustable pipette / fixed pipette. Power source: manual pipette / electric pipette. Number of working channels: single-channel pipette / multi channel pipette. special purpose: pipette, continuous dispenser accuracy, and precision accuracy-system error refers to the closeness between the measurement result you get and the real value, expressed as the error.

Generally used to indicate the size of the system error. The degree to which the measured value is close to the true value is called accuracy, and the difference between the two is called error.

Comparative Advantage

It is a common phenomenon in the operation when using the standard tips to remove the surface tension of the liquid, it is easy to leave a film on the inside surface of the tips. The residue of the liquid can lead to the inaccuracy and inconsistency of the fluid transfer results, and also lose some expensive samples. The low-adsorption head was developed to improve the common problem of liquid residue.

Advanced Fully Autoclave 8 & 12 Channel Adjustable Pipettes
Electronic Control Digital Pipette Epipette

Pipette tips are essential accessories for liquid handling instruments, and selecting the right tips is crucial for accurate and precise pipetting. Here are some general criteria to consider when choosing pipette tips:

1. Compatibility:

  • Ensure that the pipette tips are compatible with the specific pipette model you are using. Different pipette brands and models may have unique tip designs and requirements.

2. Volume Range:

  • Choose tips that cover the volume range needed for your experiments. Pipette tips are available in various sizes, from microliters to milliliters, to accommodate different sample volumes.

3. Material:

  • Pipette tips are commonly made of materials such as polypropylene or polyethylene. Consider the chemical compatibility of the tip material with your samples and reagents.

4. Sterility:

  • Depending on your application, you may need sterile or non-sterile tips. Sterile tips are crucial for applications where contamination could affect experimental results, such as cell culture or molecular biology.

5. Filter Tips:

  • For applications where aerosol contamination is a concern, consider using filter tips. These tips have a barrier that prevents liquid from entering the pipette shaft, reducing the risk of cross-contamination.

6. Tip Shape:

  • Pipette tips come in various shapes, such as universal, low-retention, or extended length. Choose the tip shape that best suits your application and minimizes sample retention.

7. Accuracy and Precision:

  • Select high-quality tips that are manufactured with precision to ensure accurate and repeatable pipetting. Tips with consistent dimensions contribute to reliable performance.

8. Graduation Marks:

  • Some pipette tips have graduation marks to help visualize the volume of liquid in the tip. This can be useful for visually confirming the presence of a liquid and avoiding over-pipetting.

9. Certifications:

  • Consider tips that meet quality standards and certifications, such as ISO certification or calibration according to industry standards. This ensures the tips are manufactured with consistent quality.

10. Packaging:

  • Pay attention to the packaging of the pipette tips. Tips should be packaged in a way that maintains their sterility and prevents contamination. Some tips come in racks, reload systems, or bulk packaging.

11. Specialty Tips:

  • Depending on your application, you might need specialty tips, such as PCR-specific tips, conductive tips for static-sensitive samples, or low-retention tips for viscous liquids.

12. Cost:

  • Consider your budget constraints while balancing the need for quality. High-quality tips are crucial for accurate pipetting, but it’s essential to find a balance that meets your requirements without unnecessary expense.

13. Environmental Impact:

  • Some manufacturers offer eco-friendly options, such as recyclable or biodegradable tips. If sustainability is a concern, explore options that align with your environmental goals.

Always refer to the manufacturer’s recommendations and guidelines for using pipette tips with specific pipette models. Additionally, conduct regular quality control checks to ensure the performance of the tips meets your laboratory’s standards.

Production Process

There are two kinds of the production processes of low-adsorption tips: physical polishing and chemical coating. The former uses polishing technology to treat the surface of the tips, which makes the surface of the tips very smooth to reduce the residual liquid and ensure the safety of the sample more reliably.

However, it cannot ensure the quality of low adsorption tips consistency. Whereas the chemical coating rule is to add a layer of the hydrophobic agent to the surface of the tips, there may be a risk of dissolution by introducing contamination. The safest and most reliable is the low adsorption head produced by Hawach Scientific can help you reduce liquid residue and improve sample recovery rate.

Materials Perspective

It is better to choose the inert material tips, which can ensure chemical compatibility and avoid dissolution. The most commonly used is pure PP material tips. There is an easy-to-judge criterion for the supplier’s use of the material, as long as you look at the color of the tips. The impurities in the tips made of recycled plastic are very easily visible to the naked eye, and when color is added, these impurities will be invisible, so the transparent tips are usually a better tip.

Appearance Perspective

Good quality pipette tips usually have a very attractive appearance. They have smooth surfaces, no burrs, smooth cuts, even shapes, and straightness. Only do that it can ensure that the liquid is not easy to remain an accurate fluid transfer.

Certificate Perspective

If the purchase is a heat-free pipette tip, the supplier should provide the certification of the batch of the product. If there is no qualified certificate, you should think twice, or choose another supplier.
These are some general criteria for the selection of pipette tips. Contact us for more suggestions on the selection of proper products.